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acetyl dipeptide 1 cetyl ester inci OPAQUE VISCOUS PALE YELLOW LIQUID WITH CHARACTERISTIC ODOR

Published October Oct 17, 2026 6:17 PM

In the evolving landscape of cosmetic science, enthusiasts and formulators alike are constantl Acetyl Dipeptide-1 Cetyl Ester in Skincare y seeking high-performance molecules that offer both comfort and structural support. One such powerhouse is Acetyl Dipeptide-1 Cetyl Ester, an ingredient that has garnered significant attention for its unique ability to serve as a "messenger of tranquility." As someone who follows cosmetic chemistry closely, I have found that understanding the technical profile of this ingredient is essential for anyone interested in advanced skincare.

Understanding the Molecule: Acetyl Dipeptide-1 Cetyl Ester

At its core, Acetyl Dipeptide-1 Cetyl Ester is a sophisticated, oil-soluble anti-ageing messenger peptide. Chemically identified by the CAS No. 196604-48-5, this molecule is composed of a dipeptide—specifically tyrosine and arginine—linked to a cetyl ester chain. This structure is critical because it significantly enhances the molecule's compatibility with the skin's lipid barrier, allowing for superior permeability compared to standard peptides.

Known widely in the industry as Calmosensine, this bioactive peptide is frequently utilized as an advanced a Acetyl Dipeptide-1 Cetyl Ester 0.3% Solution is an American-branded 3,000 ppm peptide solution for muscle relaxation & skin comfort. ctive ingredient used in co Buy Acetyl Dipeptide-1 cetyl ester -Top Manufacturer smetology. Its primary function is to provide muscle relaxation and skin comfort, effectively acting as a soothing agent.

Technical Specifications and Purity

When sourcing or evaluating this peptide, it is important to look for Acetyl Dipeptide 1 cetyl ester (trifluoroacetate salt) high-purity grades, often with a purity level of ≥98%. The raw Acetyl dipeptide 1 cetyl ester is typically presented as an Am This ingredient is present in 0.13% of cosmetics. Anti-aging night face cream (3.02%). Anti-aging day face cream (2.29%). erican-branded white peptide powder, though it is also commonly supplied as an Acetyl Dipeptide-1 Cetyl Ester 0.3% Solution.

In its solution form, you can expect an opaque viscous pale yellow liquid with a characteristic odor, typically maintained at a pH range of 6.0–8.0. Acetyl Dipeptide-1 Cetyl Ester in Skincare The molecular formula, C33H57N5O5, highlights its c Acetyl Dipeptide-1 Cetyl Ester. INCI. Acetyl Dipeptide-1 Cetyl Ester. Peptide Sequence: Ac-Tyr-Arg-O-hexadecyl ester. Molecular Formula: C33H57N5O5. Molecular  omplex synthetic nature, often produced through precise biological fermentation or chemical synthesis to ensure stability and efficacy.

The Role in Skin Architecture

Beyond its soothing properties, this ingredient is primarily used for stimulating elastin production. By supporting the structural integrity Acetyl Dipeptide-1 Cetyl Ester in Skincare of the skin, it helps prevent sagging and improves the skin's natural resistance to gravity. It is fascinating to note that it influences the expression of vital genes related to skin barrier function, such as AQP3 and FLG.

While some literature discusses Tetrapeptide-1 as a signaling peptide with antioxidant properties, the specific mechanism of our focus molecule lies in its ability to modulate the perception of comfort. It is truly a versatile component, often found in formulations that are free of formaldehyde and other common sensitizers, making it a preferred choice for sensitive skin profiles.

Integration in Cosmetic Products

If you are analyzing labels, the INCI Name: Water, Glycerin, Acetyl Dipeptide-1 Cetyl Ester is a common indicator of a stabilized, ready-to-use delivery system. It is frequently featured in:

* Anti-aging night face creams (often at concentrations around 3.02%)

* Anti-aging day face creams (around 2.29%)

* Soothing serums designed to mitigate facial stinging or discomfort

When comparing this to other popular peptides like Palmitoyl Tripeptide-1 or Acetyl Hexapeptide-8, the distinction lies in the dual-action approach: the immediate soothing "calmosensine" effect combined with the long-term structural support for elastin. Whether you see it listed under its formal INCI or as a proprietary blend like Idealift, recognizing the chemical sequence Ac-Tyr-Arg-O-hexadecyl ester ensures you are identifying the correct, high-quality active.

For those curious about the market, there are many products containing Acetyl Dipeptide 1 Cetyl Ester produced by reputable brands that prioritize high-performance, science-backed ingredients. Always ensure that the Acetyl Dipeptide-1 Cetyl Ester you choose meets the rigorous standards required for modern, effective, and comfortable personal care.

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