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decapeptide 12 sequence Its peptide sequence contains 2 tyrosines, 2 arginines and 3 serines

Published October Oct 17, 2026 10:28 PM

In the evolving field of cosmetic chemistry, understanding the precise sequence of specialized compounds is essential for those exploring modern skincare innovation Sequence, H-{DL-Tyr}-{DL-Arg}-{DL-Ser}-{DL-Arg}-{DL-Lys}-{DL-Tyr}-{DL-Ser Preview. TargetMol. Related Tags: Decapeptide-12 chemical structure | Decapeptide-12  s. Among the various compounds currently under review by researchers, Decapeptide 12 has emerged as a subject of significant interest due to its unique structural properties and its potent Sequence, H-{DL-Tyr}-{DL-Arg}-{DL-Ser}-{DL-Arg}-{DL-Lys}-{DL-Tyr}-{DL-Ser Preview. TargetMol. Related Tags: Decapeptide-12 chemical structure | Decapeptide-12  ial application in specialized topical formulations.

Decoding the Decapeptide 12 Sequence

When analyzing Decapeptide 12, it is helpful to look at its fundamental composition. While the name suggests a length of ten amino acids, technical literature often references it as a small, 12-amino acid peptide sequence in specific contexts, leading to some variations in nomenclature. However, the standard identified Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr is the recognized chain.

The sequence is frequently represented as YRSRKYSSWY or in its full form as H-Tyr-Arg-Se Decapeptide-12: Studies in Skin Cell Lightening and Anti- r-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr-OH. Variations in notation, such as H-Tyr-ArgSer-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr-OH or H2N-Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr-OH, all point to the same functional peptide.

From a chemical perspective, its structural integrity is defined by the inclusion of arginine, lysine, serine, tryptophan, and tyrosine. Specifically, its peptide sequence contains 2 tyrosines, 2 arginines and 3 serines, which contribute to its stability and physical behavior in a solution.

Technical Specifications and Characteristics

For those evaluating this peptide, understanding the verifiable technical data is key. Decapeptide-12 (often associated with the CAS number 137665-91-9) typically presents as a white to off-white powder.

* Molecular Formula: C65H90N18O17

* Molecular Weight: 1395.52 g/mol

* Standard Composition: A twelve-residue chain (though often referred to by the Decapeptide prefix) that utilizes a specific H-Tyr-Arg-Ser-Arg-. Lys-Tyr-Ser-Ser-Trp-Tyr-OH arrangement.

Because this compound is primarily synthesized for cosmetic research, quality standards are paramount. High-performance liquid chromatography (HPLC) is the standard method for verifying purity, which is typically expected to exceed 96% Decapeptide-12 is a synthetic peptide consisting of arginine, lysine, serine, tryptophan, and tyrosine. to 98% in professional-grade products.

Applications and Research Focus

The primary interest in this molecule lies in its biochemical interactions. It is primarily researched in reducing melanin production and hyperpigmentation, serving as a targeted alternative to traditional a Decapeptide-12 is an oligopeptide with proposed anti-tyrosinase activity, composed of twelve amino acids and exhibiting the sequence Try-Arg-Ser-Aar-Lysd-Tyr-  gents. By acting on the skin’s pathways, it aims to influence the appearance of tone and brightness without the complexities associated with older, more traditional chemical agents.

In my personal experience exploring high-end cosmetic ingredients, the precision of the sequence: YRSRKYSSWY is what makes this molecule stand out. Unlike broader, non-specific skincare additives, the specificity of t Decapeptide-12 his chain allows for a more focused interaction with the skin's surface.

Summary of Findings

Whether you are looking at it for its sequence or its physical characteristics, Decapeptide-12 remains a cornerstone of modern peptide re Decapeptide-12, also known by its trade name Melitane, is a synthetic decapeptide renowned in cosmetic science for its potent skin brightening and anti-  search. Its structure—composed of arginine, lysine, serine, tryptophan, and tyrosine—provides a robust framework for its use in advanced topical applications. As research continues to evolve, the focus on this small, 12-amino acid peptide sequence will likely deepen, providing further insights into how these synthetic chains can be optimized for future cosmetic advancements.

*Disclaimer: This article is for educational and informational purposes only. It does not provide medical advice, diagnosis, or treatment instructions. Always consult with a qualified professional regarding skincare concerns.*

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