In the world of peptide research and molecular chemistry, few building blocks are as fascinating as those incorporating the aromatic Phenylalanine (symbol Phe or F) is an α-amino acid with the formula C 9H 11NO 2. It is one of the four aromatic amino acids and the 21 proteinogenic amino amino acid phenylalanine. As someone who has spent significant time studying the properties of these compounds, I have found that the dipeptide phenylalanine structure serves as a cornerstone for understanding how simple molecules transition into complex, self-assembling nanostructures.
The Foundation: Phenylalanine Chemical Identity
Before diving into dipeptides, it is essential to appreciate the monomer. Phenylalanine is an essential aromatic amino acid with the molecular formula C9H11NO2. Its structural profile is defined by a benzyl side chain attached to an alpha-amino group. Whether you are looking at the standard L-isomer or specialized derivatives like L-Phenylalanine-3,3-d2 98 atom % D, the core structure remains a subject of intense academic intere phenylalanine dipeptide l-Phenylalanyl-l-alanine (Phe-Ala st.
When we discuss Diphenylalanine is the unnatural amino acid with the formula (C 6H 5) 2CHCH(NH 2)CO 2H. The compound is structurally related to the amino acids alanine and Phenylalanine, we are looking at a molecule that serves as a precursor in various biological pathways. Its structural formula: C 9 H 11 NO 2 phenylalanine is often represented in ball-and-stick models to highlight the spatial arrangement of its carbon, nitrogen, and oxygen atoms.
The Mechanics of Dipeptide Formation
A dipeptide is essentially two amino acids joined by a peptide linkage. When exploring these, I have encountered various combinations that highlight the versatility of the dipeptide phenylalanine structure.
* Phe-Ala: This is a dipeptide formed from L-phenylalanine and L-alanine residues. Its molecular representation is C12H16N2O3.
* Phe-His: This variant is composed of L-phenylalanine and L-histidine joined by a pe Phe-His is a dipeptide composed of L-phenylalanine and L-histidine joined by a peptide linkage. It has a role as a metabolite. It is functionally related to ptide linkage. It is a highly specific Catalog Number: AHF101. Synonym: H-Phe-OH. CAS Number: [63-91-2]. Molecular Weight: 165.2. Molecular Formula: C9H11NO2. * Refer to Certificate of Analysis metabolite that demonstrates how different side chains influence the behavior of dipeptides.
* Diphenylalanine (FF): Perhaps the most famous of these, Diphenylalanine (FF) represents the simplest peptide building block that self-assembles into ordered nanostructures. Its chemical formula is often contrasted with others, such as the C18H20N2O3 configuration seen in L-Phenylalanyl-L-phenylalanine.
Structural Complexity and Self-Assembly
My interest in these molecules deepened when observing how Phenylalanine's structure influences self-assembly. The structures of these dipeptides are not static; they are highly influenced by the aromatic rings of the phenylalanine residues.
In my experience, Phenylalanine's structure consists of two key components: the hydrophobic benzyl side chain and the polar alpha-amino group. This amphiphilic nature is exactly why molecules like (C 6H 5) 2CHCH(NH 2)CO 2H (the formula for certain diphenylalanine derivatives) are so effective at forming hydrogels and nanostructures.
The structural integrity of these assemblies relies on hydrogen bonding and pi-stacking interactions. When researchers analyze the formula: C9H11NO (or the corrected C9H11NO2), they are essentially mapping the potential for these molecules to behave as "molecular bricks."
Analytical Observations
Whether reviewing literature on structures of phenylalanine-containing peptides or performing hands-on analysis of phenylalanine derivat DL-Phenylalanine · Formula: C9H11NO · Molecular weight: 165.1891 · IUPAC Standard InChI: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12) ives, the precision of the molecular weight and the purity of the structural configuration are paramount. For instance, the anhydrous form of L-Phenylalanyl-L-phenylalanine has a molecular weight of 312.36, a detail that is vital when calculating stoichiometry for experimental setups.
In my personal journey with these compounds, I have found that the structural formula is only the beginning. The way these units interact—whether as part of a larger peptide sequence or as a simple dipeptide—reveals the underlying logic of molecular organization. Phenylalanine is an essential aromatic amino acid, and its role as a building block in these small, modular sequences continues to be one of the most compelling areas for anyone interested in high-purity chemical res Phenylalanine earch.