In the world of advanced skincare formulation, few ingredients generate as much interest as the copper peptide known as GHK-Cu. Whether you are a skincare enthusiast or a formulation hobbyist, navigating the technical specifications of these compounds can be complex. Understanding the nuance A framework for the safety evaluation of peptides in cosmetics s of GHK-Cu requires looking past the marketing and into the chemistry, specifically the CAS (Chemical Abstracts Service) registry numbers that define these substances.
The Chemistry of GHK-Cu: Deciphering the CAS Numbers
When researching this ingredient 070-000-251 Copper Peptide GHK-Cu, CAS 49557-75-7 , you will frequently encounter the term CAS [49557-75-7]. This is the primary identifier for the GHK tripeptide itself. However, the molecule is most effective when complexed with copper, leading to the common usage of the term GHK Cu.
It is important to distinguish between the various registry numbers associat GHK-Cu - Prezatide copper ed with this peptide. The CAS Number · 49557-75-7 is often cited in literature, while CAS No. 89030-95-5 is frequently associated with the specific copper tripeptide-1 complex used in modern cosmetic chemistry. You may also see CAS Number: 300801-03-0 or CAS #: 89030-95 GHK (Gly-His-Lys, NSC 379527, CAS Number: 49557-75-7) -5 / 300801-03-0 in various supplier catalogs. These variations often depend on whether the substance is a pure powder, a salt form like TFA, or an acetate complex.
What is a Copper Peptide?
At its core, GHK-Cu is a naturally occurring tripeptide—meaning it consists of three amino acids (Glycyl-L-histidyl-L-lysine) bound to a copper ion. This compound is first isolated from human plasma, though it can also be found in trace amounts in saliva and urine.
In the cosmetic industry, GHK-Cu Copper Tripeptide-1 CAS 89030-95-5 is prized for its unique structural properties. Because the Cu ion is central to its function, the quality of the raw material—often appearing as a distinct blue or purple powder—is vital. When sourcing, manufacturers look for high purity (often 98% or higher) to ensure stability in formulations.
Personal Experience with C CAS 89030-95-5: Ghk-Cu osmetic Formulations
Having spent time experimenting with various raw ingredients, I GHK-Cu (acetate) have found that working with Copper Peptide (GHK-Cu) requires attention to detail. The CAS RN 49557-75-7 material provides a stable foundation for those looking to create high-end topical solutions.
One observation from my own testing is the solubility of the blue copper peptide. Because it is a peptide, it is generally water-soluble, making it a versatile addition to serums. However, because copper is a reactive metal ion, it is essential to keep the pH of your final formulation within a specific range to maintain the integrity of the GHK-Cu complex.
Navigating Technical Specifications
If you are looking at a Certificate of Analysis (CoA) for a product, you might see CAS NO. 49557-75-7 listed alongside the molecular formula C14H24N6O4. Alternatively, for the complexed version, you might see CAS 89030-95-5. Understanding that these represent the same functional "blue" ingredient helps clear up the confusion often found in online forums.
Whether you refer to it as GHK-CU CAS 89030-95-5 or simply Copper Peptide, the substance remains a staple for those interested in the science of skincare. Always ensure that your supplier provides a valid MSDS (Mater GHK-Cu | C28H48CuN12O8 | CID 133697840 - PubChem ial Safety Data Sheet) referencing the correct Cas number to ensure you are receiving the high-quality material necessary for your personal projects.
By focusing on these technical identifiers, you can better navigate the market and ensure the ingredients you choose align with the standards expected in professional-grade cosmetic development. Always remember that these substances are for external cosmetic use only, as we explore the fascinating intersection of biochemistry and personal grooming.