In the specialized field of biochemical research, selecting the correct OVA peptide sequence MHC-I and MHC-II epitope peptides – catalog peptides is a foundational step for any laboratory workflow. My personal experience working with these reagents has highlighted the Ova Peptide · Name:OVA peptide (257-264) · Sequence: SIINFEKL · CAS Number: [138831-86-4] · Formula: C45H74N10O · Characteristics: None · Reference: C. M. Celluzzi Read more importance of sourcing high-purity materials, especially when dealing with model antigens derived from chicken ovalbumin protein (UniProt ID: P01012). Understanding the nuances of these s OVA Peptides equences is essential for maintaining consistency in experimental design.
Understanding the Primary OVA Peptide Sequences
When exploring a catalog peptide, researchers typically focus on two standard OVA peptides for detection use: the class I and class II epitopes. These are indispensable in immunological studies, particularly when looking at h 1 day ago—TheOVA peptide (323-339) encompasses an allergenic and antigenic epitope of the ovalbumin protein, making it a prime target for investigating Read more ow ova fragments interact with specific receptors.
The Class I Epitope: OVA (257-264)
The OVA peptide (257-264), widely known by its one-letter sequence SIINFEKL, is a H-2Kb-restricted octameric peptide. Its molecular formula is C45H74N10O, with a molecular weight of 963.13. In my experience, this is considered the gold standard for CD8+ T cell assays. Whether you are ordering from a specialized supplier or browsing a general peptide library, ensuring the trifluoroacetate salt form meets your purity requirements is critical.
The Class II Epitope: OVA (323-339)
The OVA (323-339) peptide sequence is H - Ile - Ser - Gln - Ala - Val - His - Ala - T cell epitopes presented by MHC class I molecules are typicallypeptidesbetween 8 and 11 amino acids in length and exhibiting MHC-specificsequencemotifs.Read more Ala - His - Ala Two standard OVA peptides for detection use: H-2Kb-restricted OVA class I epitope and an I-A(d)-restricted OVA class II epitope. Endotoxin-free. - Glu - Ile - Asn - Glu - Ala - Gly - Arg – OH. This ISQAVHAAHAEINEAGR sequence is a prominent antigen peptide derived from ovalbumin. It functions as a critical tool in allergy research and studies concerning major histocompatibility complex (MHC) binding. Because OVA peptide mainly exists in egg white, this synthetic version allows for precise control over concentration and binding registers, such as the I-A(d)-restricted epitope.
Navigating the Catalog: What to Look For
When you are searching for OVA (ovalbumin) peptide, you will encounter various modifications. Top-tier providers offer ovalbumin peptides labeled with biotin, TAMRA, FITC, or FAM. These labels are vital for visualization in sensitive assays.
* Purity: Always look for >95% purity to avoid interference from truncated sequences.
* Documentation: A reliable catalog peptide provider should always supply the amino acid sequence and mass spectrometry data to verify the ISQAVHAAHAEINEAGR identity.
* Application: Whether you are utilizing OVA (257-264) for OVA (ovalbumin) model research or investigating the OVA protein structure, specificity is key.
Integrating OVA Peptides into Research
The versatility of these sequences is remarkable. For instance, OVA (ovalbumin) peptide residues 257 to 280—often referred to as the OT-II peptide—is frequently used to study helper CD4+ T cell responses. When I have used high-purity OVA (257-264) peptide in my own setups, the reproducibility of the data was significantly higher compared to lower-grade alternatives.
Furthermore, the OVA peptide (323-339) is often used alongside adjuvants lik Ova (323-339) peptide - ISQAVHAAHAEINEAGR e TLR9 agonists. The interplay between the OVA antigen and immune modulators is a frequent area of interest. By using a well-characterized OVA peptide, researchers can better quantify the OVA (257-264 response profiles without the variability associated with crude extracts.
Summary of Technical Specifications
For those managing a catalog peptide inventory, keep these data points for OVA peptide (323-339) handy:
* Sequence: Ile-Ser-Gln-Ala-Val-His-Ala-Ala-His-Ala-Glu-Ile-Asn-Glu-Ala-Gly-Arg
* Formula: C74H121N27O24
* Molecular Weight: 1772.9 (approximate)
By maintaining a rigorous focus on the amino acid sequence and verifying the OVA (323-339) or OVA (257-264 purity, you ensure that your research remains robust. These peptides are the bedrock of modern antigen-specific studies, and selecting the right ova variant from a trusted catalog peptide source is the best way to ensure long-term success in your projects. Whether you are focused on ovalbumin peptide (257-264) or the longer class II variants, precision in your choice of OVA peptide is the first step Ova Peptide · Name:OVA peptide (257-264) · Sequence: SIINFEKL · CAS Number: [138831-86-4] · Formula: C45H74N10O · Characteristics: None · Reference: C. M. Celluzzi Read more toward high-quality results.