In the specialized field of laboratory research, the P21 peptide has garnered significant attention for its role as a neurotrophic mimetic. As someone who follows the latest developments in synthetic research compounds, I have found that navigating the technical data—particularly the CAS number—is essential for ensuring the integrity of any experimental setup. When sourcing compounds for study, clarity regarding chemical identifiers is the first step in verifying the substance’s identity.
Defining the P21 Peptide and Its Chemical Identity
The P21 peptide (often referred to as P021 or Peptide 021) is a synthetic tetrapeptide derived from the biologically active region of ciliary neurotrophic factor (CNTF), specifically spanning amino acid residues 148–151. P21 is a small tetra-peptide that has become a subject of interest in neurobiology laboratories.
One of the most common points of confusion in the research community involves the CAS No. While searching for this compound, you will often encounter the identifier 1246751-68-7. This is the most frequently cited CAS number associated with the primary synthetic version of the peptide. However, researchers should remain diligent, as some catalogs list CAS Number: 1394011-91-6 or even CAS Number. 1174043-81-0 depending on the specific synthesis method or salt form, such as BAT-009965. In some instances, particularly with proprietary formulations, the CAS Number, Not assigned or CAS number: N/A is noted, emphasizing t P21, also designated as P021 or Peptide 6, represents a synthetically engineered tetrapeptide mimetic of ciliary neurotrophic factor (CNTF) with potent he importance of relying on analytical documentation like HPLC and COA reports rather than just the registry number alone.
Technical Specifications and Structural Characteristics
P21 is a synthetic tetrapeptide composed of four amino acids linked by peptide bonds, designed to mimic the neurogenic properties of CNTF. Its molecular formula is typically represented as C27H42N6O8, with a molecular weight of approximately 578.66 g/mol.
For those managing a lab, understanding the physical properties is crucial:
* Form: Typically found as a lyophilized (freeze-dried) powder.
* Storage: Most research standards suggest storing the peptide at -20°C to maintain stability.
* Purity: High-quality p21 peptide samples for research should ideally demonstrate a purity of ≥98% via HPLC.
The Role of P21 in Laboratory Research
P21 serves as a valuable research tool for investigators exploring neuroplasticity and signaling pathways. Because P21 is a nootropic peptide that functions as a mimetic of endogenous factors, it is frequently utilized in studies involving neurotrophin signaling.
When reviewing literature or sourcing materials, you might see references to P21 (also referred to as P-021). It is important to distinguish this from the native p21 protein (CIP1/WAF1), which is a cyclin-dependent kinase inhibitor involved in cell cycle regulation. P-21 is a synthetic neuroprotective peptide that operates distinctly from the tumor-suppressor protein.
Best Practices for Sourcing Research Peptides
If you are looking to acquire this compound for your laboratory, always prioritize suppliers who provide a Certificate of Analysis (COA) that explicitly references the 1246751-68-7 identifier if applicable. Because the CAS Number: Not publicly registered status is common for P21, also designated as P021 or Peptide 6, represents a synthetically engineered tetrapeptide mimetic of ciliary neurotrophic factor (CNTF) with potent newer or modified synthetic variants, the burden of verification often falls on the lead investigator.
Always check that your source provides:
1. Mass Spectrometry Data: To verify the molecular weight (578.66 g/mol).
2. HPLC Purity Reports: To confirm the absence of impurities.
3. Endotoxin Testing: Essential for ensuring the compound is suitable for sensitive experimental models.
By maintaining rigorous P21 (10mg) | Research Peptide, 99% Purity standar P21 Peptide for Sale | USA Made | Buy Now! ds and understanding the nuances of the p21 peptide documentation, researchers can ensure their work remains consistent and reproducible. Whether you are investigating the 1246751-68-7 variant or a specific ac P21 is a small tetra-peptide derived from the most active region of CNTF (ciliary neurotrophic factor), the amino acid residues 148-151. It is involved in the etate salt, the commitment to analytical transparency is what defines high-q P21 Peptide uality research. Product Name · P21 Peptide ; CAS Number · 1246751-68-7 ; Sequence · Ac-Asp-Gly-Gly-Adm-Leu-NH2 ; Molecular Formula · C27H42N6O8 ; Molecular Weight · 578.66.