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palmitoyl pentapeptide 4 sequence Sequence

Published October Oct 17, 2026 2:37 PM

When exploring the world of advanced cosmetic ingredients, one name consistently surfaces Palmitoyl pentapeptide-4 ; Chemical formula. C39H75N7O ; Molar mass, 802.068 g·mol ; Except where otherwise noted, data are given for materials in their standard  in high-performance formulations: Palmitoyl Pentapep Matrixyl Palmitoyl Pentapeptide-4 214047-00-4 - Sinoway tide-4. For those of us who prioritize ingredient integrity in our personal care routines, understanding the structural composition of this molecule is essential. Often recognized by its commercia Palmitoyl Pentapeptide-4 Powder (CAS No.: 214047-00-4) l designation, Matrixyl, this bioactive compound has earned its reputation as a cornerstone in topical aesthetics.

Decoding the Chemical Structure

The effectiveness of this ingredient lies in its specific sequence. Biochemically, it is a synthetic peptide where a palmitoyl group—a long-chain fatty acid—is chemically linked to a pentapeptide sequence. This lipophilic modification is crucial because it enhances the molecule's ability to interact with the skin's surface, improving overall delivery and efficacy.

The primary amino acid string defining CAS Number. 214047-00-4 · Name. PalMitoyl Pentapeptide-4 · Sequence. Pal-Lys-Thr-Thr-Lys-Ser · Molecular Structure · Molecular Formula · Molecular Weight. 802.05  this Palmitoyl Pentapeptide-4 is lysine-threonine-threonine-lysine-serine. In scientific literature and technical data sheets, you will frequently Palmitoyl pentapeptide 4 see this represented as Pal-Lys-Thr-Thr-Lys-Ser-OH or the abbreviated form, Pal-KTTKS.

Key technical specifications include:

* CAS Number: 214047-00-4

* Molecular Formula: C39H75N7O10

* Molecular Weight: Approximately 802.05 g/mol

* Standard Nomenclature: Pal-Lys-Thr-Thr-Lys-Ser

Biological Signaling and Function

Why is this specific Palmitoyl Pentapeptide so highly regarded? It functions as a "signal peptide." Research suggests that it acts as a precursor sequence fragment of type I collagen. By mimicking the structure of natural skin components, it stimulates collagen production, which is why it is widely celebrated for its role in promoting skin health and rejuvenation.

It is important to note that while the standard Palmitoyl Pentapeptide-4 is associated with the KTTKS sequence, some studies indicate it is associated with two sequences, KTTKS and KTSKS, depending on the specific synthesis profile. This versatility highlights why it is a synthetic cosmetic ingredient widely used in skincare products across the globe.

Personal Experience and Application

From my experience integrating this into my routine, I have found that the stability of the Palmitoyl-Lys-Thr-Thr-Lys-Ser-OH complex makes it a reliable addition to any topical regimen. Because it is a small, biologically active molecu GS-PepFirming™ Palmitoyl Pentapeptide-4 le, it does not require complex delivery systems to be effective.

When searching for products containing this ingredient, you will often see it listed as {Pal}-Lys-Thr-Thr-Lys-Ser. Whether you are looking for a concentrated serum or a sophisticated cream, the presence of Palmitoyl Pentapeptide 4 ensures that the formula is designed with a focus on skin texture and resilience.

Final Thoughts for Enthusiasts

As someone who meticulously reviews ingredient lists, I find the precision of Palmitoyl Pentapeptide-4 to be fascinating. It is a testament to how synthetic chemistry can mirror natural processes to support the skin's architecture. Whether you refer to it by its full chemical name, Palmitoyl-Lys-Thr-Thr-Lys-Ser-OH, or its shorthand Pal-KTTK Palmitoyl Pentapeptide-4 | Active Pharmaceutical Ingredients S, it remains a gold standard in the industry for those pursuing a disciplined approach to skincare.

Always ensure you are sourcing your products from reputable manufacturers who adhere to high purity standards, as the efficacy of this 4-series peptide is highly dependent on the quality of the synthesis. By focusing on proven ingredients like this, you can better navigate the crowded landscape of modern cosmetic science.

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