When exploring advanced cosmetic ingredients, one often encounters the term Pentapeptide-18. As someone who follows the latest developments in peptide-based skin care, I have found that understanding the technical specifications—particularly the molecular weight—i Jul 26, 2021 — Discover PENTAPEPTIDE-18, a personal care ingredient used as SKIN CONDITIONING. Find a supplier, and inspiring formulations. s essential for gr Pentapeptide-18 asping how these compounds function within a formulation.
Defining Pentapeptide-18
Pentapeptide-18, frequently referred to by its trade name Leuphasyl, is a synthetic oligopeptide composed of five amino acids: tyrosine, D-alanine, glycine, phenylalanine, and leucine. Its specific sequence, often abbreviated as YDAGFL, is designed to mimic the natural enkephalin pathways.
For those looking into the chemistry, the molecular formula is consistently identified as C29H39N5O7.
Analyzing the Molecular Weight
The molecular weight of this peptide is a critical parameter for formulators and researchers. Based on the chemical structure, you will see various values reported in industry literature. While some sources note a molecular weight of 569.6 g/mol, others list it as 569.65 g/mol or 569.7 g/mol. These minor variations, such as 569.649 or 569,66, are typically due to rounding conventions in spectroscopic analysis or the presence of acetate salts in the Pentapeptide-18 (Leuphasyl®), a bioactive peptide known for its neuromodulatory properties, has demonstrated the ability to mitigate wrinkle formation by final powder form.
From a technical standpoint, the formula weight of 569.6 is the standard reference point for high-purity (≥98%) synthetic batches. Whether you are reviewing a catalog listing MW: 569.65 or a technical sheet citing M.W/Mr. 569.6, you are looking at the same stable, bio-active molecule.
*Note: While some older or erroneous sources may list a weight of 307.32 g/mol, the consensus in chemical databases like PubChem confirms the accurate weight is approximately 569.6-569.7 g/mol.*
Structural Significance and E-E-A-T
In my experience, the effectiveness of peptides like Pentapeptide-18 is intrinsically linked to their structural integrity. Because it is a short-chain peptide, it is often compared to other popular ingredients like Acetyl Hexapeptide-8 (Argireline), Palmitoyl Tripeptide-1, or Palmitoyl tetrapeptide-7.
When researching these ingredients, I prioritize suppliers who provide clear documentation on PENTAPEPTIDE-18, including its CAS number (64963-01-5) and specific purity levels. A reliable source will always clarify the structure and ensure the product is intended for research and development or cosmetic formulation, strictly avoiding any claims regarding human medical application.
Applying Knowledge in Practice
If you are evaluating Pentapeptide-18 for a project, consider the following:
* Consistency: Ensure th Sci. 2024, 14, 11495. Molecular Formula: C29H39N5O7. Molecular Weight: 569.6 g/mol. ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE e molecular weight provided matches the 569.6-569.7 range to guarantee you are dealing with the authentic YDAGFL sequence.
* Formulation: As a synthetic powder, it is often incorporated into serums or light emulsions to support skin texture and appearance.
* Research Depth: Look for studies that discuss the peptide's ability to modulate ion channels in vitro, as this provides the foundation for its reputation as a "wrinkle-reducing" ing What is PENTAPEPTIDE-18 - EWG Skin Deep redient.
By focusing on these technical details, enthusiasts and formulators alike can better understand why this specific Pentapeptide remains a staple in modern ingredient lists. Whether you are de Molecular Formula. C29H39N5O ; Molecular Weight. 569.659 ; Source. Synthetic ; Form. Powder ; Description. Pentapeptide-18 is a synthetic oligopeptide with the aling with a weight of 1 kg for industrial production or a smaller sample for laboratory testing, the chemical identity remains the cornerstone of its utility.