Navigating the world of biochemical research requires precision, especially when identifying specific compounds. One of the most critical identifiers for any researcher is the CAS Number. Whether you are working with a Poly(peptide): Synthesis, Structure, and Function of - PMC simple peptide or a complex polypeptide, these unique numerical A polypeptide is a single linear chain of many amino acids (any length), held together by amide bonds. · A protein consists of one or more polypeptides (more identifiers act as the fingerprint for chemical substances. In my own experience sourcing materials for laboratory studies, I have found that verifying the CAS No. is the first step toward ensuring experimental reproducibility.
The Role of CAS Numbers in Peptide Identification
A CAS Number (Chemical Abstracts Service) provides a unambiguous way to identify a specific chemical substance, regardless of the various synonyms or trade names it might carry. For instance, when searching for Pancreatic Polypeptide, Human (CAS: 7 Fmoc Amino Acids for Solid Phase Peptide Synthesis (SPPS) 5976-10-2), having the exact identifier prevents confusion with other variants or biological oligomers.
In my work, I frequently encounter materials like RGD (Arg-Gly-Asp) Peptides, which are essential for studying cell adhesion motifs. Knowing the specific CAS Number: 99896-85-2 (or related identifiers for specific salt forms LZ1 peptide - (CAS 1423743-97-8) ) allows me to cross-reference purity and structural data with databases like PubChem.
Key Identifiers and Their Applications
When reviewing technical documentation, you will often see a variety of formats. Here are some examples of how these identifiers appear in professional literature:
* Pancreatic Polypeptid Pancreatic Polypeptide (human) ; Purity, ≥95% (HPLC) ; CAS Number, 75976-10-2 ; PubChem ID, 24868176 ; InChI Key, HFDKKNHCYWNNNQ-YOGANYHLSA-N ; Smiles e (human): Identified by CAS Number, 75976-10-2, this is a critical molecule in NPY receptor research.
* Beta-Amyloid Peptide (1-42): Frequently referenced by CAS number 107761-42-2, which is essential for characterizing its molecular weight and empirical formula.
* Synthetic Substrates: Molecules like the LZ1 peptide car Pancreatic Polypeptide (human) ; Purity, ≥95% (HPLC) ; CAS Number, 75976-10-2 ; PubChem ID, 24868176 ; InChI Key, HFDKKNHCYWNNNQ-YOGANYHLSA-N ; Smiles ry the CAS No.: 1423743-97-8, highlighting the importance of cataloging even the most niche synthetic compounds.
Why Accuracy Matters in Peptide Synthesis
In the realm of peptide chemistry, structural integrity is paramount. Whether you are performing Solid Phase Peptide Synthesis (SPPS) using reagents like Fmoc-Gly-OH (CAS Number: 29022-11-5) or analyzing a complex protein chain, the CAS No ensures that the starting materials meet the required purity standards—often $\ge95\%$ or higher.
I have observed that reputable suppliers, such as those associated with the PolyPeptide Group or PolyPeptide Labs, prioritize these identifiers to maintain transparency. When you examine a Certificate of Analysis (CoA), you are essentially confirming that the polypeptide in your hand matches the documented CAS profile.
Navigating Technical Data
If you are just beginning to curate your laboratory inventory, keep these tips in mind:
1. Always verify the CAS: Do not rely on common names alone. A peptide can have multiple modifications, and each modification may have a different CAS number.
2. Check the Chemical Structure: Use the CAS No to pull the chemical formula and molecular weight from trusted scientific databases. For example, understanding that a specific polypeptide has a specific molecular weight helps in calculating molarity for your assays.
3. Storage and Handling: Many, such as those with CAS number: 59763-91-6, require specific environmental controls to prevent degradation.
Conclusion: A Commitment to Research Integrity
My journey into the science of biological polymers has taught me that the CAS No is more than just a label—it is a foundation for legitimate, verifiable research. Whether you are investigating the peptide bond or evaluating the synthesis of a novel polypeptide, maintaining a rigorous database of these identifiers is a hallmark of a disciplined researcher.
By prioritizing the use of accurate CAS identifiers, we ensure that our work remains consistent, reproducible, and aligned with the global standards of the life s In stock peptides for research | Life Sciences ciences community. Always remember that for any polypeptide, the CAS number. 107761-42-2 ; Purity. >95% ; Form. Solid. See storage information ; Molecular weight. 4514 Da ; Molecular formula. C203H311N55O60S CAS No is your most reliable guide to identifying the right material for your specific research goals.